Di-µ-(1-(3-(1H-imidazol-1-yl)propyl)-2-methyl-4-oxo-1,4-dihydropyridin-3-olate)-bis[(η5-pentamethylcyclopentadienyl)iridium(III)] Chloride

Ilya A. Shutkov; Nikolai A. Melnichuk; Konstantin A. Lyssenko; Nataliya E. Borisova; Olga N. Kovaleva; Alexey A. Nazarov

doi:10.3390/M1816

Molbank (May 2024)

Di-µ-(1-(3-(1H-imidazol-1-yl)propyl)-2-methyl-4-oxo-1,4-dihydropyridin-3-olate)-bis[(η5-pentamethylcyclopentadienyl)iridium(III)] Chloride

Ilya A. Shutkov,
Nikolai A. Melnichuk,
Konstantin A. Lyssenko,
Nataliya E. Borisova,
Olga N. Kovaleva,
Alexey A. Nazarov

Affiliations

Ilya A. Shutkov: Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia
Nikolai A. Melnichuk: Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia
Konstantin A. Lyssenko: Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia
Nataliya E. Borisova: Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia
Olga N. Kovaleva: Faculty of General Medicine, N.I. Pirogov Russian National Research Medical University, Ostrovitianov Str. 1, 117513 Moscow, Russia
Alexey A. Nazarov: Department of Chemistry, M.V. Lomonosov Moscow State University, Leninskie Gory 1/3, 119991 Moscow, Russia

DOI: https://doi.org/10.3390/M1816
Journal volume & issue: Vol. 2024, no. 2
p. M1816

Abstract

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A metallacyclic maltol-tethered organometallic Ir(III) half-sandwich complex was synthesized as an analog of the ruthenium anticancer complexes (RAPTA/RAED) to evaluate its in vitro antiproliferative activity against various human cancer cell lines.

Published in Molbank

ISSN: 1422-8599 (Online)
Publisher: MDPI AG
Country of publisher: Switzerland
LCC subjects: Science: Chemistry: Inorganic chemistry
Website: https://www.mdpi.com/journal/molbank

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