Management of adult patients with alcoholic liver disease: clinical guidelines of the Russian Scientific Liver Society

Abstract

The aim of publication. To present clinical guidelines of the Russian Scientific Liver Society on diagnosis and treatment of alcoholic liver disease to general practitioners. Summary. Harmful alcohol intake is the burning issue for Russia. The alcoholic liver disease (ALD) is a clinical and morphological entity that encompasses several forms of the liver parenchyma lesions resulting from alcohol abuse, that range from steatosis to alcoholic hepatitis (steatohepatitis) followed by progression to fibrosis, liver cirrhosis and hepatocellular carcinoma. Alcoholic liver cirrhosis gives significant impact to digestive disease associated motility. Alcohol addiction screening may be carried out by estimation of the standard doses of alcohol, application of CAGE and AUDIT questionnaires. Gamma-glutamyltranspeptidase activity and the level of carbohydrate-deficient transferrin are recommended to verify regular alcohol abuse in clinical practice. Abstinence from alcohol is the first line and the basic therapeutic procedure for any form and stage of ALD. Short therapeutic interventions practice helps to cope with alcoholic issue at any stage, gives the chance to motivate the patient, including the treatment of addiction to alcohol, intake of drugs. Specific pharmaceutical therapy is carried out at alcoholic hepatitis in relation to severity and alcoholic liver cirrhosis. Conclusion. The amount of consumed alcohol and drinking pattern should be systematized in clinical practice of the doctor of any specialty, first of all - for patients with liver diseases. Life prognosis estimation, ALD treatment are selected according to the stage and severity and aimed to decline in ALD-related motility.

Keywords

• алкогольная болезнь печени
• опросник cage
• опросник audit
• индекс мэддрея
• тиамин
• адеметионин
• эссенциальные фосфолипиды