EMBO Molecular Medicine (May 2021)

PI3Kα targeting, nipping pancreatic cancer evolution in the bud

  • Glancis Luzeena Raja Arul,
  • Martin E Fernandez‐Zapico

DOI
https://doi.org/10.15252/emmm.202114362
Journal volume & issue
Vol. 13, no. 7
pp. 1 – 3

Abstract

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Abstract Thibault et al (2021) elucidate key signalling events mediating metastatic evolution in pancreatic ductal adenocarcinoma (PDAC) by demonstrating a role of PI3Kα in the regulation of macro‐metastatic disease and a corresponding pro‐tumoural immune response supporting disease progression.