Anais Brasileiros de Dermatologia (Aug 2017)

Do you know this syndrome? Heerfordt-Waldenström syndrome

  • Rafael Cavanellas Fraga,
  • Priscila Kakizaki,
  • Neusa Yuriko Sakai Valente,
  • Larissa Karine Leite Portocarrero,
  • Mônica Fernandes Senise Teixeira,
  • Priscilla Fernandes Senise

DOI
https://doi.org/10.1590/abd1806-4841.20175211
Journal volume & issue
Vol. 92, no. 4
pp. 571 – 572

Abstract

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Abstract: Heerfordt-Waldenström syndrome is a rare subacute variant of sarcoidosis, characterized by enlargement of the parotid or salivary glands, facial nerve paralysis and anterior uveitis. Granulomas with a peripheral lymphocyte deficit are found in the anatomic pathology of affected organs. It is normally self-limiting, with cure achieved between 12 and 36 months, but some prolonged cases have been reported. Diagnosis of the syndrome is clinical, and treatment depends on the degree of systemic impairment. Oral corticosteroids represent the first line treatment option. The mortality rate ranges between 1 and 5% of cases.

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