Nature Communications (Jun 2021)

Olfactory expression of trace amine-associated receptors requires cooperative cis-acting enhancers

  • Ami Shah,
  • Madison Ratkowski,
  • Alessandro Rosa,
  • Paul Feinstein,
  • Thomas Bozza

DOI
https://doi.org/10.1038/s41467-021-23824-3
Journal volume & issue
Vol. 12, no. 1
pp. 1 – 12

Abstract

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How olfactory sensory neurons express one allele of one TAAR gene is not well understood. Here the authors identify two cooperative cis-acting enhancers that govern TAAR gene choice and that share both similarities and differences with known olfactory enhancers.