The phenomenon of associated Graves' and Plummer's disease: A case report

Abstract

We have presented the case of a female patient with the simultaneous occurrence of autoimmune hyperthyroidism (Graves' disease) and autonomous hyperthyroidism (Plummer's disease). She has been under our care for euthyroid goiter for many years, but when last seen it was noted that she showed signs of 'hyperthyroid syndrome'. We carried out extensive examination and testing. The diagnosis of associated two types of hyperthyroidisms was based on the following criteria: features of clinical hypermetabolic state, maximal suppression of TSH, raised 'free' thyroxin and presence of TSH receptor autoantibodies, associated with scintigraphic findings of 'hot' nodules with partially suppressed paranodal tissue. In this paper we discussed our previous experiences and compared them to those of other authors.

Keywords

• graves' disease
• plummer's disease
• hyperthyroidism
• associated appearance