Journal of Personalized Medicine (Dec 2021)

Recommendations for the Diagnosis and Treatment of Multiple Sclerosis Relapses

  • Cristina Ramo-Tello,
  • Yolanda Blanco,
  • Luis Brieva,
  • Bonaventura Casanova,
  • Eva Martínez-Cáceres,
  • Daniel Ontaneda,
  • Lluís Ramió-Torrentá,
  • Àlex Rovira

Journal volume & issue
Vol. 12, no. 1
p. 6


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Minimizing the risk of relapse is essential in multiple sclerosis (MS). As none of the treatments currently available are capable of completely preventing relapses, treatment of these episodes remains a cornerstone of MS care. The objective of this manuscript is to reduce uncertainty and improve quality of care of this neurological process. This article addresses definitions of key concepts, recommendations for clinical examination, classification criteria, magnetic resonance imaging, biomarkers, and specific therapeutic counsels including special populations such as pregnant and breastfeeding women, and children. An algorithm for treating MS relapses is also provided.