Lupus nephropathy

Abstract

Lupus nephritis (LN) occurs between 30% and 70% of patients with systemic lupus erythematosus (SLE), depending on race and sex. LN appears early in the disease with prevalence of severe forms such as classes III, IV and mixed (V + III IV or V +). 50% of adults and 70% of children with lupus born in Colombia, suffer LN sometime in their lifetime; in this population 25% of children and 38% of adults have nephrotic syndrome. The remission rate at six months is low, the proteinuria in nephrotic range, and the incraease of baseline creatinine predict failure to achieve remission at 6 months.

Keywords

• Lupus
• Nephritis
• Nephrotic Syndrome
• Proliferative glomerulonephritis.