COVID-19-associated rhino-orbital- cerebral mixed mycoses with intracranial fungal granuloma – An aggressively managed rare entity

Abstract

Rhino-orbital-cerebral mucormycosis (ROCM) with intracranial extension is a fatal disease. A case of extensive ROCM, with rare intracranial fungal granuloma, seen in a COVID-19 positive young male is described. A successful therapy consisting of a multidisciplinary approach for sinuses debridement, orbital exenteration, and intracranial granuloma excision was done. Nonseptate hyphae of Mucor and septate filamentous Aspergillus grew concurrently from exenterated orbital specimen.

Keywords

• aspergillus
• intracranial fungal granuloma
• mucor
• rhino-orbital-cerebral mucormycosis