Kidney & Blood Pressure Research (Apr 2014)

Quantitative Analysis of Abdominal Aortic Calcification in CKD Patients Without Dialysis Therapy by Use of the Agatston Score

  • Mitsuru Ichii,
  • Eiji Ishimura,
  • Hideaki Shima,
  • Yoshiteru Ohno,
  • Akinobu Ochi,
  • Shinya Nakatani,
  • Akihiro Tsuda,
  • Shoichi Ehara,
  • Katsuhito Mori,
  • Shinya Fukumoto,
  • Toshihide Naganuma,
  • Yoshiaki Takemoto,
  • Tatsuya Nakatani,
  • Masaaki Inaba

DOI
https://doi.org/10.1159/000355768
Journal volume & issue
Vol. 38, no. 2-3
pp. 196 – 204

Abstract

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Background/Aim: The aim of the present study was to quantitatively examine factors associated with aortic calcification in non-dialysis CKD patients. Methods: We quantitatively investigated aortic calcification from the renal artery to the bifurcation in 149 non-dialysis CKD patients (58±16 years; 96 males and 53 females, 48 diabetics; eGFR 40.3±29.3 ml/min), and measured Agatston scores using multi-slice computed tomography. Result: Of 149 patients, aortic calcification was present in 117. In patients with aortic calcification, age (pConclusions: Hyperphospatemia, chronic inflammation, diabetes, and decreased GFR are associated significantly with the presence of aortic calcification in non-dialysis CKD patients. Decreased eGFR was associated significantly and independently with the quantitative degree of aortic calcification.

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