Mediators of Inflammation (Jan 2012)

The PBDE-209 Exposure during Pregnancy and Lactation Impairs Immune Function in Rats

  • Xianbao Liu,
  • Hong Zhan,
  • Xu Zeng,
  • Chunfang Zhang,
  • Dunjin Chen

DOI
https://doi.org/10.1155/2012/692467
Journal volume & issue
Vol. 2012

Abstract

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In the present study, we assessed the treatment effects of PBDE-209 administration on the immune function in rats during pregnancy and lactation. We harvested the blood and organs for flow cytometry, viability assay, enzyme-linked immunosorbent assay, and histological evaluation. The results of this study were the PBDE-209 exposure during pregnancy and lactation impairs immune function in rats. The results may contribute to understanding the mechanism of PBDE-209 in immune function.