A case of gastric polyposis in antral area of stomach following prolonged proton-pump therapy

Abstract

We describe the clinical scenario of a young male with history of non ulcer dyspepsia who had endoscopic evidence of gastric polyposis in antral area. The polyps disappeared four months after proton pump inhibitors were stopped. Proton pump inhibitors have been linked to gastric fundal polyposis and not antral gland polyposis. This is the first report originating from an Asian country describing antral gland polyposis (AGPs) in a patient on long-term PPI therapy with no evidence of Helicobacter pylori. A case report with brief review is presented.

Keywords

• proton pump inhibitors
• hyperplastic gastric polyps
• antral gland polyps
• Helicobacter pylori