Microbiologia Medica (Jun 2008)

Isolation of multidrug-resistant Enterobacter cloacae and comparison among clavulanate-tazobactam and sulbactam-synergy by using a double-disk synergy test

  • Vincenzo Savini,
  • Fabio Febbo,
  • Andrea Balbinot,
  • Marzia Talia,
  • Chiara Catavitello,
  • Assunta Manna,
  • Fabio Di Berardino,
  • Francesca Fioritoni,
  • Daniela Carlino,
  • Giovanni Di Bonaventura,
  • Domenico D’Antonio

DOI
https://doi.org/10.4081/mm.2008.2587
Journal volume & issue
Vol. 23, no. 2

Abstract

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False negative results of double-disk synergy test with Enterobacter cloacae are common, as AmpC-enzymes may mask ESBLs elaboration. We increased the sensitivity of the method by using both clavulanate- and tazobactam/sulbactam; hence, we suggest to use all the three inhibitors to screen ESBLs in AmpC ß-lactamases producing organisms.

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