The 11th Italian Quantum Information Science conference (IQIS 2018) took place in Catania, Italy, at the Monastero dei Benedettini, from September 17 to 20, 2018. IQIS 2018 was organized by the Department of Physics and Astronomy “E. Majorana” of the University of Catania, and by IMM-CNR, Catania. The conference also hosted an event dedicated to the FET-Flagship 2018/28 on Quantum Technologies. These proceedings collect papers contributed by the participants, which extend presentations delivered at the conference, and were subjected to peer-reviewing. They provide a snapshot of the contributions (mainly, but only) by the Italian scientific community to the developing field of quantum information and related subjects.