PLoS ONE (Jan 2023)

Association between parental absence during childhood and metabolic syndrome during adulthood: A cross-sectional study in rural Khanh Hoa, Vietnam.

  • Rachana Manandhar Shrestha,
  • Tetsuya Mizoue,
  • Thuy Thi Phuong Pham,
  • Ami Fukunaga,
  • Dong Van Hoang,
  • Chau Que Nguyen,
  • Danh Cong Phan,
  • Masahiko Hachiya,
  • Dong Van Huynh,
  • Huy Xuan Le,
  • Hung Thai Do,
  • Yosuke Inoue

DOI
https://doi.org/10.1371/journal.pone.0282731
Journal volume & issue
Vol. 18, no. 3
p. e0282731

Abstract

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BackgroundThis study aimed to determine the association between parental absence during childhood and metabolic syndrome (MetS) in adulthood among middle-aged adults in rural Khanh Hoa province, Vietnam. Given that broader literature on adverse childhood experiences (ACEs) suggests a strong positive association between ACEs and cardiometabolic risk or diseases, we hypothesized that parental absence during childhood, which is a major component of ACEs, is more likely to cause MetS in adulthood.MethodsData were obtained from the baseline survey of the Khanh Hoa Cardiovascular Study, in which 3000 residents aged between 40 to 60 years participated. MetS was assessed using the modified Adult Treatment Panel III (ATP III) criteria. It was considered parental absence if the participants had experienced parental absence due to death, divorce, or out-migration before three or between three to 15 years. We used multiple logistic regression analyses to examine the association between parental absence during childhood and metabolic syndrome during adulthood.ResultsThere was no significant association between parental absence and MetS; adjusted odds ratio [AOR] was 0.97 (95% confidence interval [CI] = 0.76-1.22) for those who experienced parental absence between three to 15 years and the corresponding figure for those who experienced it before three years was 0.93 (95% CI = 0.72-1.20). No significant associations were observed when these were examined for the causes of parental absence.ConclusionThis study did not support our hypothesis of an association between parental absence during childhood and metabolic syndrome during adulthood. Parental absence may not be a predictor of MetS among Vietnamese people in rural communities.