Clinical, Cosmetic and Investigational Dermatology (Jul 2023)
An Unexpected Finding: Treatment History Associated with the Quality of Life in Chinese Patients with Port-Wine Stains
Abstract
Qian Zhao,1– 3,* Lian Liu,1,3,* Xiaoxue Li,1,3 Lihua Yang,1,3 Xian Jiang1,3 1Department of Dermatology, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China; 2Department of Medical Cosmetology, Chengdu Second People’s Hospital, Chengdu, Sichuan, 610021, People’s Republic of China; 3Laboratory of Dermatology, Clinical Institute of Inflammation and Immunology (CIII), Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu, 610041, People’s Republic of China*These authors contributed equally to this workCorrespondence: Xian Jiang, Department of Dermatology, West China Hospital, Sichuan University, 37 Guoxue Alley, Wuhou District, Chengdu, Sichuan, 610041, People’s Republic of China, Email [email protected]: Port-wine stains (PWS) are predominantly located on the face and neck. Hence, PWS affect not only aesthetic appearance but may also cause psychological distress. However, very few studies have researched on the quality of life (QoL) in Chinese patients with PWS.Aim: To evaluate QoL in patients with PWS.Methods and Materials: Skindex-29 and Dermatology Life Quality Index (DLQI) were used to investigate the QoL of the patients with PWS and healthy controls.Results: In total, 198 adults with PWS and 200 healthy controls were included. The scores of symptomatic, emotional and functional dimensions of Skindex-29 in the observational group were significantly higher as compared with the control group (P< 0.05). Female gender, lesion location and the treatment history (such as pulsed dye laser or photodynamic therapy) had a negative impact on the scores (emotional and functional dimensions) of the patients with PWS. The median DLQI score was 3 points in the observational group and 0 points in the control group (P< 0.05), and QoL of patients who had a history of previous treatments was diminished.Conclusion: The QoL of patients with PWS is impaired. Patients’ QoL is negatively influenced by female gender, lesion location and treatment history. The Skindex-29 scale seems to be more applicable to the study of QoL of patients with PWS.Keywords: port-wine stains, quality of life, Skindex-29, dermatology life quality index
