Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1

Wen-Lin Su; Chih-Pei Lin; Hui-Ching Hang; Ping-Sheng Wu; Ching-Feng Cheng; You-Chen Chao

Journal of Microbiology, Immunology and Infection (Feb 2021)

Desaturation and heme elevation during COVID-19 infection: A potential prognostic factor of heme oxygenase-1

Wen-Lin Su,
Chih-Pei Lin,
Hui-Ching Hang,
Ping-Sheng Wu,
Ching-Feng Cheng,
You-Chen Chao

Affiliations

Wen-Lin Su: Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan; School of Medicine, Tzu Chi University, Hualien, Taiwan
Chih-Pei Lin: School of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Pathology and Laboratory Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan
Hui-Ching Hang: Department of Pathology and Laboratory Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan
Ping-Sheng Wu: School of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan
Ching-Feng Cheng: School of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei, Taiwan
You-Chen Chao: School of Medicine, Tzu Chi University, Hualien, Taiwan; Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City, Taiwan; Corresponding author. Department of Internal Medicine, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, 289 Jianguo Rd, Xindian Dist., New Taipei City 23142, Taiwan, ROC. Fax: +886 2 66289009.

Journal volume & issue: Vol. 54, no. 1
pp. 113 – 116

Abstract

Read online

Increased heme levels, anemia, and desaturation occur during infection. We aimed to compare the levels of heme, heme oxygenase-1 (HO-1), ferritin, and bilirubin in coronavirus disease 2019 (COVID-19) patients at different saturation levels. Heme and HO-1 enzyme levels significantly increased in the low SpO2 group, but further studies are required.

Published in Journal of Microbiology, Immunology and Infection

ISSN: 1684-1182 (Print)
Publisher: Elsevier
Country of publisher: Hong Kong
LCC subjects: Science: Microbiology
Website: https://www.sciencedirect.com/journal/journal-of-microbiology-immunology-and-infection

About the journal

Abstract

Keywords