Radiology Case Reports (Aug 2024)

Disseminated mycobacterium avium complex spinal osteomyelitis in a patient with interferon gamma receptor deficiency: A case report

  • Sarah Jaggernauth, BS,
  • Andrew Waack, BS,
  • Alastair Hoyt, MD,
  • Jason Schroeder, MD

Journal volume & issue
Vol. 19, no. 8
pp. 3070 – 3075

Abstract

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Disseminated mycobacterium avium complex (MAC) infection is rare and is classically associated with immunodeficient states. Osteomyelitis is a rare manifestation of disseminated MAC infection. The overwhelming majority of MAC infections occur in patients with human immunodeficiency virus (HIV). Disseminated MAC infection has been described in interferon gamma receptor deficiency, an immunodeficiency mechanistically linked to mycobacterial infection. We present a case of disseminated MAC vertebral osteomyelitis in a patient with interferon gamma receptor deficiency.

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