Man-Made Synthetic Receptors for Capture and Analysis of Ochratoxin A

Abstract

Contemporary analytical methods have the sensitivity required for Ochratoxin A detection and quantification, but direct application of these methods on real samples can be rarely performed because of matrix complexity. Thus, efficient sample pre-treatment methods are needed. Recent years have seen the increasing use of artificial recognition systems as a viable alternative to natural receptors, because these materials seem to be particularly suitable for applications where selectivity for Ochratoxin A is essential. In this review, molecularly imprinted polymers, aptamers and tailor-made peptides for Ochratoxin A capture and analysis with particular attention to solid phase extraction applications will be discussed.

Keywords

• mycotoxin
• Ochratoxin A
• molecularly imprinted polymer
• aptamer
• oligosorbent
• peptide library
• binding peptide
• solid phase extraction