Lamellar Keratoplasty Using Acellular Bioengineering Cornea (BioCorneaVet<sup>TM</sup>) for the Treatment of Feline Corneal Sequestrum: A Retrospective Study of 62 Eyes (2018–2021)
Huihao Xu,
John S. Sapienza,
Yipeng Jin,
Jiahao Lin,
Xiaobo Zheng,
Haodi Dong,
Hongxiu Diao,
Ying Zhao,
Jiafeng Gao,
Jing Tang,
Xueqian Feng,
Danielle Micceri,
Haoran Zeng,
Degui Lin
Affiliations
Huihao Xu
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
John S. Sapienza
Long Island Veterinary Specialists, Plainview, NY 11803, USA
Yipeng Jin
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
Jiahao Lin
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
Xiaobo Zheng
College of Veterinary Medicine, Southwest University, No. 160, Xueyuan Road, Rongchang District, Chongqing 402460, China
Haodi Dong
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
Hongxiu Diao
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
Ying Zhao
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
Jiafeng Gao
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
Jing Tang
College of Veterinary Medicine, Southwest University, No. 160, Xueyuan Road, Rongchang District, Chongqing 402460, China
Xueqian Feng
College of Veterinary Medicine, Southwest University, No. 160, Xueyuan Road, Rongchang District, Chongqing 402460, China
Danielle Micceri
Long Island Veterinary Specialists, Plainview, NY 11803, USA
Haoran Zeng
College of Veterinary Medicine, Southwest University, No. 160, Xueyuan Road, Rongchang District, Chongqing 402460, China
Degui Lin
College of Veterinary Medicine, China Agricultural University, No. 2, Yuanmingyuan West Road, Haidian District, Beijing 100193, China
To retrospectively evaluate the effectiveness and outcome of lamellar keratoplasty using acellular bioengineering cornea (BioCorneaVetTM) for the treatment of feline corneal sequestrum (FCS). The medical records of cats diagnosed with FCS that underwent lamellar keratoplasty with BioCorneaVetTM between 2018 and 2021 with a minimum of 3 months of follow-up were reviewed. Follow-up examinations were performed weekly for 3 months, and then optical coherence tomography (OCT) examination was performed on select patients at 0, 3, 6, and 12 months post-operatively. A total of 61 cats (30 left eyes and 32 right eyes) were included. The Persian breed was overrepresented, 48/61 (78.69%). Four different thicknesses of acellular bioengineering cornea were used (200, 300, 400, or 450 microns), and the mean graft size was 8.23 mm (range, 5.00–12.00 mm). Minor complications were composed of partial dehiscence, and protrusion of the graft occurred in 7/62 eyes (11.29%). The median postoperative follow-up was 12.00 months (range, 3–41 months). A good visual outcome was achieved in 60/62 eyes (96.77%), and a mild to moderate corneal opacification occurred in 2/62 (3.23%). No recurrence of corneal sequestrum was observed. From the results, lamellar keratoplasty using acellular bioengineering cornea (BioCorneaVetTM) is an effective treatment for FCS, providing a good tectonic support and natural collagen framework, and resulting in satisfactory visual and cosmetic effects.
