Фармакокинетика и Фармакодинамика (Apr 2014)
Isoform CYP1A2, as a part of the cytochrome P450 superfamily
Abstract
The role of cytochrome P450 isoforms CYP1A2 and in the metabolism of caffeine is described. Caffeine pharmacokinetics data in humans and laboratory animals are presented. Examples of drug-drug interactions of cubstrate marker caffeine with different drugs are given.