Фармакокинетика и Фармакодинамика (Apr 2014)

Isoform CYP1A2, as a part of the cytochrome P450 superfamily

  • Y. G. Novickaya,
  • V. P. Zherdev,
  • A. O. Viglinskaya,
  • A. A. Litvin

Journal volume & issue
Vol. 0, no. 1
pp. 4 – 13

Abstract

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The role of cytochrome P450 isoforms CYP1A2 and in the metabolism of caffeine is described. Caffeine pharmacokinetics data in humans and laboratory animals are presented. Examples of drug-drug interactions of cubstrate marker caffeine with different drugs are given.

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