Copper-Promoted Hiyama Cross-Coupling of Arylsilanes With Thiuram Reagents: A Facile Synthesis of Aryl Dithiocarbamates

Yiying Wang; Hongtao Shen; Jianhua Qiu; Mengqi Chen; Weimin Song; Mingqin Zhao; Longfei Wang; Feng Bai; Hongxia Wang; Zhiyong Wu

doi:10.3389/fchem.2022.867806

Frontiers in Chemistry (Apr 2022)

Copper-Promoted Hiyama Cross-Coupling of Arylsilanes With Thiuram Reagents: A Facile Synthesis of Aryl Dithiocarbamates

Yiying Wang,
Hongtao Shen,
Jianhua Qiu,
Mengqi Chen,
Weimin Song,
Mingqin Zhao,
Longfei Wang,
Feng Bai,
Hongxia Wang,
Zhiyong Wu

Affiliations

Yiying Wang: Flavors and Fragrance Engineering and Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou, China
Hongtao Shen: Technology Center, China Tobacco Henan Industrial Co., Ltd., Zhengzhou, China
Jianhua Qiu: Technology Center, China Tobacco Henan Industrial Co., Ltd., Zhengzhou, China
Mengqi Chen: Technology Center, China Tobacco Henan Industrial Co., Ltd., Zhengzhou, China
Weimin Song: Technology Center, China Tobacco Henan Industrial Co., Ltd., Zhengzhou, China
Mingqin Zhao: Flavors and Fragrance Engineering and Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou, China
Longfei Wang: Flavors and Fragrance Engineering and Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou, China
Feng Bai: Technology Center, China Tobacco Henan Industrial Co., Ltd., Zhengzhou, China
Hongxia Wang: Technology Center, China Tobacco Henan Industrial Co., Ltd., Zhengzhou, China
Zhiyong Wu: Flavors and Fragrance Engineering and Technology Research Center of Henan Province, College of Tobacco Science, Henan Agricultural University, Zhengzhou, China

DOI: https://doi.org/10.3389/fchem.2022.867806
Journal volume & issue: Vol. 10

Abstract

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We report herein a facile Hiyama cross-coupling reaction of arylsilanes with thiuram reagents (tetraalkylthiuram disulfides or tetraalkylthiuram monosulfide) enabled by copper fluoride. Compared to our previous work, this protocol is an alternative protocol for the generation of S-aryl dithiocarbamates. It features low toxic and readily available substrates, cost-effective promoter, easy performance, and provides good yields.

Published in Frontiers in Chemistry

ISSN: 2296-2646 (Online)
Publisher: Frontiers Media S.A.
Country of publisher: Switzerland
LCC subjects: Science: Chemistry
Website: http://journal.frontiersin.org/journal/chemistry

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