Nature Communications (Jul 2019)

Optogenetic control of Bacillus subtilis gene expression

  • Sebastian M. Castillo-Hair,
  • Elliot A. Baerman,
  • Masaya Fujita,
  • Oleg A. Igoshin,
  • Jeffrey J. Tabor

DOI
https://doi.org/10.1038/s41467-019-10906-6
Journal volume & issue
Vol. 10, no. 1
pp. 1 – 11

Abstract

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Bacillus subtilis has complex spatial and temporal gene expression patterns but currently lacks optogenetic tools to explore these processes. Here the authors import and debug a cyanobacterial green light sensor pathway and show that it enables precise optical control of gene expression.