Scientific African (Nov 2019)

Evaluation of the antioxidant and cytotoxic activities of zinc oxide nanoparticles synthesized using scutellaria baicalensis root

  • C.O. Tettey,
  • H.M. Shin

Journal volume & issue
Vol. 6

Abstract

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The authors describe a simple green method for the preparation of zinc oxide nanoparticles (ZnONPs) using the aqueous root extract of Scutellaria baicalensis. The synthesized ZnONPs were characterized by UV–Vis spectroscopy, FTIR, TEM, SEM and EDX. They were spherical in shape and with sizes ranging from 33.14–99.03 nm. The ZnONPs produced exhibited significant free radical scavenging effects. An in-vitro study showed a dose-dependent cytotoxic effect on HeLa cells. Keywords: Green synthesis, Scutellaria baicalensis, ZnONPs, Antioxidants, Cytotoxicity