The Role of Vitamin D in the Pathogenesis of Allergic Rhinitis and Atopy

Abstract

The aim of this work is to analyze and compare the discussions about the relationship between vitamin D and allergic rhinitis and the symptoms of atopy. Most investigators analyze its role as a mediator in the provision of an adequate immune response. Its effect, not only on allergic, but also on some neoplastic, autoimmune and cardiovascular disorders is widely discussed. However, many questions regarding its activity remain unclear and extensive research in this area will be crucial for our understanding of both the physiological role and its potential therapeutic effect for a number of immune and inflammatory diseases. Undoubtedly proven is the influence of vitamin D on different cells of the immune system. Finally, the authors draw conclusions on current knowledge about the possibilities of influencing the vitamin D in the pathogenesis of allergic reactions.

Keywords

• vitamin d
• allergic rhinitis
• atopy
• immune system