IUCrData (Jul 2016)

11β-Hydroxymedroxyprogesterone

  • Sharifah Nurfazilah Wan Yusop,
  • Sadia Sultan,
  • Bohari M. Yamin,
  • Syed Adnan Ali Shah,
  • Humera Naz

DOI
https://doi.org/10.1107/S2414314616010750
Journal volume & issue
Vol. 1, no. 7
p. x161075

Abstract

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The title compound, C22H32O4, a fungal-transformed metabolite of medroxyprogesterone, comprises one cyclohexanone ring, two cyclohexane rings and one cyclopentane ring fused together. The cyclohexanone ring has a half-chair conformation, while the cyclohexane rings possess chair conformations and the cyclopentane ring has a twisted conformation on the fused C—C bond. In the crystal, molecules are linked by strong O—H...O and also C—H...O hydrogen bonds, creating a two-dimensional network parallel to (10-1).

Keywords