We proposed a novel approach based on a complementary split-ring resonator metamaterial in a two-port MIMO antenna, giving high gain, multiband results with miniature size. We have also analyzed a circular disk metasurface design. The designs are also defected using ground structure by reducing the width of the ground plane to 8 mm and etching all other parts of the ground plane. The electric length of the proposed design is 0.5λ × 0.35λ × 0.02λ. The design results are also investigated for a different variation of complementary split-ring resonator ring sizes. The inner and outer ring diameters are varied to find the optimized solution for enhanced output performance parameters. Good isolation is also achieved for both bands. The gain and directivity results are also presented. The results are compared for isolation, gain, structure size, and the number of ports. The compact, multiband, high gain and high isolation design can apply to WiMAX, WLAN, and satellite communication applications.