BIO Integration (Jul 2024)
Can Nanocrystals Help Create Our Dream Cosmetics?
Abstract
Cosmetics have evolved beyond mere skin beautifying agents. Cosmetics are now combined with active ingredients to support skin health. This evolution underpins the emergence of dream cosmetics, where innovation is continuously pursued. Indeed, nanotechnology has responded in force to the notion of dream cosmetics. Nanocrystals are expected to overcome the barriers posed by issues, such as poor solubility of bioactive agents and skin penetration. Moreover, nanocrystals exhibit multiple features, making dream cosmetics achievable. However, the clinical translation of nanocrystals is hampered by concern of negative host responses associated with long-term use. Accordingly, screening by integrated omics is needed because because multiple omics offer comprehensive nanotoxicity evaluation by identifying new molecular pathways and toxicity markers.
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