Cell Reports (Apr 2024)
Differentiating the human heart: A focus on atrioventricular canal cardiomyocytes
Abstract
Bioengineering of a functional human heart continues to face many challenges, including the production of distinct cardiac cell types. Now, in Cell Stem Cell, Ye et al.1 develop AVC-like cardiomyocytes through timing- and concentration-specific activation of canonical Wnt signaling.