Cell Reports (Apr 2024)

Differentiating the human heart: A focus on atrioventricular canal cardiomyocytes

  • Paige Takasugi,
  • Li Qian

Journal volume & issue
Vol. 43, no. 4
p. 114085

Abstract

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Bioengineering of a functional human heart continues to face many challenges, including the production of distinct cardiac cell types. Now, in Cell Stem Cell, Ye et al.1 develop AVC-like cardiomyocytes through timing- and concentration-specific activation of canonical Wnt signaling.