PLoS ONE (Jan 2021)

Teenage pregnancy as a risk factor for placental abruption: Findings from the prospective Japan environment and children's study.

  • Hyo Kyozuka,
  • Tsuyoshi Murata,
  • Toma Fukusda,
  • Akiko Yamaguchi,
  • Aya Kanno,
  • Shun Yasuda,
  • Akiko Sato,
  • Yuka Ogata,
  • Yuta Endo,
  • Mitsuaki Hosoya,
  • Seiji Yasumura,
  • Koichi Hashimoto,
  • Hidekazu Nishigori,
  • Keiya Fujimori,
  • Japan Environment and Children’s Study (JECS) Group

DOI
https://doi.org/10.1371/journal.pone.0251428
Journal volume & issue
Vol. 16, no. 5
p. e0251428

Abstract

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ObjectivePlacental abruption is a significant obstetric complication that affects both maternal and neonatal mortality and morbidity. The present study examined the effect of maternal age on the incidence of placental abruption.MethodsWe used data of singleton pregnancies from the Japan Environment and Children's Study, which was a prospective birth cohort study conducted between January 2011 and March 2014 across 15 regional centers in Japan. A multiple regression model was used to identify whether maternal age (ResultsA total of 94,410 Japanese women (93,994 without placental abruption and 416 with placental abruption) were recruited. Herein, 764, 8421, 25915, 33517, and 25793 women were aged ConclusionsIn the Japanese general population, besides advanced maternal age, teenage pregnancy was associated with placental abruption. Recently, the mean maternal age has been changing in Japan. Therefore, it is important for obstetric care providers to provide proper counseling to young women based on up-to-date evidence.