Evaluation of the Oral Microcirculation in Patients Undergoing Anti COVID-19 Vaccination: A Preliminary Study
Adriana Acquaro,
Giorgia Brusca,
Sofia Casella,
Enzo Maria Cumbo,
Antonio Della Valle,
Mohmed Isaqali Karobari,
Giuseppe Marino,
Anand Marya,
Pietro Messina,
Giuseppe Alessandro Scardina,
Domenico Tegolo,
Antonino Tocco,
Cesare Valenti
Affiliations
Adriana Acquaro
Department of Surgical Oncological and Stomatological Disciplines, University of Palermo, 90127 Palermo, Italy
Giorgia Brusca
Department of Surgical Oncological and Stomatological Disciplines, University of Palermo, 90127 Palermo, Italy
Sofia Casella
Department of Surgical Oncological and Stomatological Disciplines, University of Palermo, 90127 Palermo, Italy
Enzo Maria Cumbo
Department of Surgical Oncological and Stomatological Disciplines, University of Palermo, 90127 Palermo, Italy
Antonio Della Valle
Department of Surgical Oncological and Stomatological Disciplines, University of Palermo, 90127 Palermo, Italy
Mohmed Isaqali Karobari
Department of Conservative Dentistry & Endodontics, Saveetha Dental College & Hospitals, Saveetha Institute of Medical and Technical Sciences University, Chennai 600077, Tamil Nadu, India
Giuseppe Marino
Department of Mathematics and Informatics, University of Palermo, 90123 Palermo, Italy
Anand Marya
Department of Orthodontics, University of Puthisastra, Phnom Penh 12211, Cambodia
Pietro Messina
Department of Surgical Oncological and Stomatological Disciplines, University of Palermo, 90127 Palermo, Italy
Giuseppe Alessandro Scardina
Department of Surgical Oncological and Stomatological Disciplines, University of Palermo, 90127 Palermo, Italy
Domenico Tegolo
Department of Mathematics and Informatics, University of Palermo, 90123 Palermo, Italy
Antonino Tocco
Department of Mathematics and Informatics, University of Palermo, 90123 Palermo, Italy
Cesare Valenti
Department of Mathematics and Informatics, University of Palermo, 90123 Palermo, Italy
Videocapillaroscopy allows the study of both the morphological and architectural structure of the microcirculation and its hemodynamic conditions; these parameters are directly involved in autoimmune and/or inflammatory pathologies. The purpose of this research, based on capillaroscopy, is to establish whether a patient who receives an anti-COVID 19 vaccine has any changes in their oral microcirculation. A complete capillaroscopic mapping of the oral cavity of the subjects examined was made; the investigated mucosa sites were the following: cheek, labial, chewing-gingival and back of the tongue. This study showed an increase in capillary density from the comparison between the mean labial capillary density of vaccinated patients and the reference mean capillary density value of the literature. The increase in capillary density is a sign that can be attributed to an increase in angiogenic activity. The EMA, GACVS and MHRA have reviewed the risk of thrombosis after vaccination, agreeing that the benefits outweigh the risks.
