Nature Communications (Mar 2016)
Three-dimensional structural dynamics and fluctuations of DNA-nanogold conjugates by individual-particle electron tomography
Abstract
The control of DNA-mediated assembly depends on a precise understanding of the three-dimensional structure of DNA-nanocrystal-hybridized building blocks. Here, the authors use cryo-electron microscopy and negative-staining techniques to investigate the morphology of DNA-nanogold conjugates.