Development strategy and trend of medical magnesium alloy implant materials

Abstract

Magnesium alloys features excellent biological safety, biological induction, biocompatibility and valuable self-degradability, which leads to its broad clinical application prospects in the field of bone implantation and cardiovascular stents. In this paper, the research progress of medical magnesium alloy in recent years was systematically reviewed in four aspects: alloying, preparation methods, heat treatment and surface modification. The basic principles, technical advantages and disadvantages of various processes and surface modification methods were mainly analysed, and their effects on the microstructure and properties of magnesium alloys were summarized. In order to break the limitations of clinical application of magnesium alloy, the best development strategy of medical magnesium alloy implant materials was proposed: on the one hand, effectively match with the mechanical behaviour of natural bone tissue through the synergistic coupling of alloying, preparation and heat treatment; on the other hand, precisely regulate the degradation rate of magnesium alloy through the modification of the surface. It has become the main development trend for the surface modification technology of magnesium alloy in the future that two or more surface modification techniques are combined and interacted to achieve multi-function requirements.

Keywords

• medical magnesium alloy
• implant material
• collaborative coupling of processes
• combination and interaction