Mutation in the FUS nuclear localisation signal domain causes neurodevelopmental and systemic metabolic alterations

• Zeinab Ali,
• Juan M. Godoy-Corchuelo,
• Aurea B. Martins-Bach,
• Irene Garcia-Toledo,
• Luis C. Fernández-Beltrán,
• Remya R. Nair,
• Shoshana Spring,
• Brian J. Nieman,
• Irene Jimenez-Coca,
• Rasneer S. Bains,
• Hamish Forrest,
• Jason P. Lerch,
• Karla L. Miller,
• Elizabeth M. C. Fisher,
• Thomas J. Cunningham,
• Silvia Corrochano

Affiliations

Zeinab Ali

Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain

Juan M. Godoy-Corchuelo

Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain

Aurea B. Martins-Bach

Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford OX3 9D, UK

Irene Garcia-Toledo

Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain

Luis C. Fernández-Beltrán

Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain

Remya R. Nair

Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford OX1 3PT, UK

Shoshana Spring

Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON M57 3H7, Canada

Brian J. Nieman

Mouse Imaging Centre, The Hospital for Sick Children, Toronto, ON M57 3H7, Canada

Irene Jimenez-Coca

Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain

Rasneer S. Bains

Mary Lyon Centre at MRC Harwell, Didcot, Oxfordshire OX11 ORD, UK

Hamish Forrest

Mary Lyon Centre at MRC Harwell, Didcot, Oxfordshire OX11 ORD, UK

Jason P. Lerch

Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford OX3 9D, UK

Karla L. Miller

Wellcome Centre for Integrative Neuroimaging, University of Oxford, Oxford OX3 9D, UK

Elizabeth M. C. Fisher

Department of Neuromuscular Diseases, UCL Queen Square Institute of Neurology, London WC1N 3BG, UK

Thomas J. Cunningham

Mammalian Genetics Unit, MRC Harwell Institute, Didcot, Oxfordshire OX11 ORD, UK

Silvia Corrochano

Neurological Disorders Group, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria Hospital Clínico San Carlos (IdiSSC), Madrid 28040, Spain