Research progress in comprehensive and sequential treatment of tongue squamous cell carcinoma

Abstract

Tongue squamous cell carcinoma (TSCC) is the most common oral cancer, with early lymph node metasta⁃ sis and poor prognosis. Surgery is the primary treatment based on sequential therapy for TSCC. The treatment of TSCC has evolved gradually in the past few years and has exhibited a trend of standardization and personalization. Several as⁃ pects of TSCC treatment are discussed in this article, such as surgery, radiotherapy, chemotherapy, biotherapy, function⁃ al rehabilitation, psychological rehabilitative treatment, prognosis and follow⁃up systems. This article comments on the types of treatments and research progress for TSCC in China and abroad with the aim of providing a better understand⁃ ing and references for clinical treatment.

Keywords

• Tongue squamous cell carcinoma
• Surgery
• Cervical lymph node dissection
• Functional reconstruc⁃ tion
• Radiotherapy
• Chemotherapy
• Biotherapy
• Comprehensive and sequential treatment