Mitochondrial Pharmacotherapeutics - Advancements and Applications

Abstract

Mitochondria, known as the “powerhouse of the cell”, plays an important role in the occurrence of multiple diseases and disorders. Mitochondria are believed to come into existence from the synergistic relationship between the proto-eukaryotic and primitive prokaryotic efficient by oxidative phosphorylation. It is the major hub of Adenosine Tri Phosphate production through the implementation of oxidative phosphorylation. It is the processing unit of the “Electron transport chain”. Mitochondria is useful in dealing with various cancers, cardiovascular problems, fatty-acid oxidation disorders, and several kinds of tumours and also several cancers.

Keywords

• mitochondria
• evolution
• therapy
• reactive oxygen species
• apoptosis