Nature Communications (Aug 2018)

Dietary stearic acid regulates mitochondria in vivo in humans

  • Deniz Senyilmaz-Tiebe,
  • Daniel H. Pfaff,
  • Sam Virtue,
  • Kathrin V. Schwarz,
  • Thomas Fleming,
  • Sandro Altamura,
  • Martina U. Muckenthaler,
  • Jürgen G. Okun,
  • Antonio Vidal-Puig,
  • Peter Nawroth,
  • Aurelio A. Teleman

DOI
https://doi.org/10.1038/s41467-018-05614-6
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 10

Abstract

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Dietary fatty acids have different effects on human health. Here, the authors show that ingestion of the fatty acid C18:0, but not of C16:0, rapidly leads to fusion of mitochondria and fatty acid oxidation in humans, possibly explaining the health benefits of C18:0.