310 T cell intrinsic DNA damage and repair response as a novel marker associated with clinical response to PD-1 blockade

• Alexander Huang,
• Claire Friedman,
• Yuki Muroyama,
• Sasikanth Manne,
• Divij Mathew,
• Lakshmi Chilukuri,
• Allison Greenplate,
• Ramin Herati,
• E John Wherry,
• Derek Oldridge,
• Caiyue Xu,
• Dimitriy Zamarin

Affiliations

Alexander Huang

2University Health Network – Toronto General Hospital, Toronto, Canada

Claire Friedman

Aff1 grid.51462.340000000121719952Memorial Sloan Kettering Cancer Center 300 E 66th Street, BAIC 813 10065 New York NY USA

Yuki Muroyama

1University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

Sasikanth Manne

1University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

Divij Mathew

1University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

Lakshmi Chilukuri

1University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

Allison Greenplate

1University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA

Ramin Herati

3 Divison of Infectious Disease and Immunology and NYU Langone Vaccine Center, Department of Medicine, New York University School of Medicine, New York, NY, USA

E John Wherry

2University of Pennsylvania, Philadelphia, PA, USA

Derek Oldridge

2Children’s Hospital of Philadelphia, Philadelphia, PA, USA

Caiyue Xu

4University of Pennsylvania, Philadelphia, PA, USA

Dimitriy Zamarin

6Memorial Sloan Kettering Cancer Center, New York, NY, USA