Case Reports in Pathology (2020-01-01)

Metaplastic Carcinoma of the Breast with Squamous Differentiation: A Case Report from the University Teaching Hospital of Kigali (CHUK), Rwanda

  • Delphine Uwamariya,
  • Carine Nyampinga,
  • Anne Yvette Nsenguwera,
  • Belson Rugwizangoga

Journal volume & issue
Vol. 2020


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Metaplastic breast carcinoma is a rare and aggressive condition, accounting less than 1% of breast malignancies. It presents with large mass and frequently with distant metastasis at time of diagnosis. Morphologically, it is characterized by the differentiation of neoplastic epithelium into epithelial or mesenchymal-looking elements like squamous cells, spindle cells, cartilage, or bone and has poor prognosis with its triple negative status.