Significance of MiRNA-34a and MiRNA-192 as a risk factor for nonalcoholic fatty liver disease

Abstract

Highlights ● NAFLD is deliberated a complicated health problem owing to its growing prevalence, complex pathogenesis, and difficulty to diagnose. ● It is crucial to find an efficient noninvasive and affordable biomarker for earlier identification and staging of NAFLD. ● Ultimate role of miRNA-34a in lipid metabolism dysregulation may lead to NAFLD. ● MiRNA-34a and MiRNA-192 are broadly stated to play a role in the development of NAFLD and NASH.

Keywords

• Nonalcoholic fatty liver disease (NAFLD)
• Gene expression
• microRNAs (miRNAs)
• MiRNA-34a
• miRNA-192