Effect of different physical activity intensities on hematopoietic stem cells CD34+ and relationship with some of cardiovascular risk factors in women

Abstract

Purpose: The purpose of this study was to determine the effect of two different intensities of exerciseon hematopoietic stem cells and relationship with some of cardiovascular risk factors in women.Methods: Fourteen female students from a group volunteers (group 1: mean age 22 ±2 years, BMI20.81±1.91 kg.m2, n = 7. group 2: mean age 21 ±2 years, BMI 20.38 ± 1.66 kg/m2, n = 7) wererandomly selected via questionnaire and each group ran 30 minutes at their (60-75% of Vo2max) ontreadmill. Blood samples were taken from all subjects for measurement of hematopoietic stem cellsCD34+ and same Isotype control ratio LDL/HDL and Ch/HDL and triglyceride before and 10 minutesafter the test. The related t-test (paired) were used for comparisons within a group. To comparevariables between the groups were used multivariate analysis of variance test (MANOVA). Fordetermining the relationship between variables Pearson correlation coefficient were used. Statisticalsignificance was accepted as P<0.05. Results: Results of this study showed that both intensities ofexercise increased significantly the number of CD34+ cells, this effect was higher in intensity of 75%VO2max, but was not statistically significant. No significant correlation between CD34+ and ratioLDL/HDL and Ch/HDL and triglyceride was observed. Conclusions: according to the findings thepresent study can be expressed that physical activity with intensity 60% and 75% VO2max can increasere-enthotelialisation due to mobilization of CD34+ cells.

Keywords

• hematopoietic stem cells cd34+
• exercise intensity
• ratio ldl/hdl
• ch/hdl
• triglyceride