Evaluation of the clinical efficacy of local antibacterial therapy in the treatment of acute bacterial rhinosinusitis

Abstract

Aim.To evaluate the clinical efficacy of Polydexa with phenylephrinum in the complex treatment of moderate acute bacterial rhinosinusitis. Materials and methods.The article presents the results of a clinical study of 100 patients with moderate acute bacterial rhinosinusitis 37 (37%) men, 63 (63%) women aged 15 to 53 years. The patients were randomized into 2 groups of 50 people each. In the study group, patients received systemic antibiotic therapy and a topical nasal spray of Polydexa with phenylephrinum. The control group received systemic antibacterial therapy and long-acting local decongestants. The evaluation criteria were statistically significant differences in clinical and laboratory parameters of the control and main groups. Results and conclusion.The pronounced anti-inflammatory, antimicrobial effects of the drug were confirmed; conclusions were drawn about the clinical efficacy, tolerability, safety of Polydexa with phenylephrinum and allows to achieve complete resolution of the pathological process in more cases.

Keywords

• acute sinusitis
• rhinosinusitis
• antibiotic therapy
• local therapy
• polydexa with phenylephrinum