Conjugated Dienones from Differently Substituted Cinnamaldehyde as Highly Potent Monoamine Oxidase‑B Inhibitors: Synthesis, Biochemistry, and Computational Chemistry

• Bijo Mathew,
• Jong Min Oh,
• Mohamed A. Abdelgawad,
• Ahmed Khames,
• Mohammed M. Ghoneim,
• Sunil Kumar,
• Lekshmi R. Nath,
• Sachithra Thazhathuveedu Sudevan,
• Della Grace Thomas Parambi,
• Clement Agoni,
• Mahmoud E. S. Soliman,
• Hoon Kim

Affiliations

Bijo Mathew

Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India

Jong Min Oh

Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea

Mohamed A. Abdelgawad

Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Al Jouf, Saudi Arabia

Ahmed Khames

Department of Pharmaceutics and Industrial Pharmacy, College of Pharmacy, Taif University, Taif, Saudi Arabia

Mohammed M. Ghoneim

Department of Pharmacy Practice, Faculty of Pharmacy, AlMaarefa University, Ad Diriyah, Saudi Arabia

Sunil Kumar

Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India

Lekshmi R. Nath

Department of Pharmacognosy, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India

Sachithra Thazhathuveedu Sudevan

Department of Pharmaceutical Chemistry, Amrita School of Pharmacy, Amrita Vishwa Vidyapeetham, Kochi, India

Della Grace Thomas Parambi

Department of Pharmaceutical Chemistry, College of Pharmacy, Jouf University, Sakaka, Al Jouf, Saudi Arabia

Clement Agoni

Molecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa

Mahmoud E. S. Soliman

Molecular Bio-Computation and Drug Design Laboratory, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa

Hoon Kim

Department of Pharmacy, and Research Institute of Life Pharmaceutical Sciences, Sunchon National University, Suncheon, Republic of Korea