Evaluation of the Toxic Effect of <i>Bauhinia purpurea</i> Mediated Synthesized Silver Nanoparticles against <i>In-vitro</i> and <i>In-vivo</i> Models
Nagarajan Shobana,
Pandurangan Prakash,
Antony V. Samrot,
Subramanian Saigeetha,
Mahendran Sathiyasree,
Rajendran Thirugnanasambandam,
Sridevi Visvanathan,
Basanta Kumar Mohanty,
Gokul Shankar Sabesan,
Shanmugaboopathi Dhiva,
Rajan Renuka Remya,
Senthilkumar Pachiyappan,
Samraj Wilson
Affiliations
Nagarajan Shobana
Department of Biotechnology, School of Bio and Chemical Engineering, Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India
Pandurangan Prakash
Department of Biotechnology, School of Bio and Chemical Engineering, Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India
Antony V. Samrot
School of Bioscience, Faculty of Medicine, Bioscience and Nursing, MAHSA University, Jenjarom 42610, Selangor, Malaysia
Subramanian Saigeetha
Department of Biotechnology, School of Biosciences and Technology, Vellore Institute of Technology, Vellore 632014, Tamil Nadu, India
Mahendran Sathiyasree
Department of Biotechnology, School of Bio and Chemical Engineering, Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India
Rajendran Thirugnanasambandam
Centre for Ocean Research (DST—FIST Sponsored Centre), MoES—Earth Science & Technology Cell, Sathyabama Institute of Science and Technology, Chennai 600119, Tamil Nadu, India
Sridevi Visvanathan
Unit of Biochemistry, Faculty of Medicine, AIMST University, Semeling, Bedong 08100, Kedah Darul Aman, Malaysia
Basanta Kumar Mohanty
Faculty of Medicine, Manipal University College Malaysia (MUCM), Jalan Padang Jambu, Bukit Baru 75150, Melaka, Malaysia
Gokul Shankar Sabesan
Faculty of Medicine, Manipal University College Malaysia (MUCM), Jalan Padang Jambu, Bukit Baru 75150, Melaka, Malaysia
Shanmugaboopathi Dhiva
Department of Microbiology, Sree Narayana College, Alathur, Palakkad 678682, Kerala, India
Rajan Renuka Remya
Department of Biotechnology, Bharath Institute of Higher Education and Research, Bharath University, Chennai 600073, Tamil Nadu, India
Senthilkumar Pachiyappan
Department of Chemical Engineering, Saveetha Engineering College, Thandalam, Chennai 602105, Tamil Nadu, India
Samraj Wilson
Department of Botany, St. John’s College, Tirunelveli 627002, Tamil Nadu, India
Metal nanoparticles, such as gold nanoparticles, silver nanoparticles, etc., have many benefits and have been in use for a very long time. Nevertheless, a number of concerns have been raised about the environmental impact and the possibility of exposure to various living systems at the moment. Thus, in this study, silver nanoparticles were synthesized by using plant gum from Bauhinia purpurea and characterization was done using UV—Visible Spectroscopy, Scanning Electron Microscopy, X—ray Diffraction, etc. To determine the accumulation and toxic effects caused by the nanoparticles, Eudrilus eugeniae, Danio rerio, and their embryos were exposed to the synthesized silver nanoparticles and evaluated using microscopic observation, histology, and Inductively Coupled Plasma Optical Emission Spectrometry (ICP—OES).
