Advanced Biomedical Research (Jan 2023)

Is chronic kidney disease, a predictor of in-hospital mortality in Coronavirus Disease 2019 (COVID-19) patients?

  • Firouzeh Moeinzadeh,
  • Vahideh Raeisi,
  • Media Babahajiani,
  • Mojgan Mortazavi,
  • Samaneh Pourajam,
  • Shiva Seirafian,
  • Mohammad Shirzadi,
  • Shahram Taheri,
  • Mehrdad Salahi,
  • Marjan Mansourian,
  • Arash Toghyani,
  • Zahra Zamani

DOI
https://doi.org/10.4103/abr.abr_352_21
Journal volume & issue
Vol. 12, no. 1
pp. 39 – 39

Abstract

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Background: Chronic kidney disease (CKD) is an important comorbidity in Coronavirus Disease 2019 (COVID-19) patients considering its high prevalence. We aimed to figure out the relationship between CKD and COVID-19 mortality in this study. Materials and Methods: In total, 116 CKD patients (estimated glomerular filtration rate [eGFR] lower than 60 mL/min/1.73 m2) and 147 control subjects confirmed with COVID-19 were studied. Data regarding demographics, sign and symptoms, laboratory findings, and chest computed tomography were collected. Association between CKD and in-hospital mortality were analyzed using logistic regression models adjusted for confounders. Results: Mortality rate was significantly higher in CKD than non-CKD (30.17 vs 4.76, P 0.05) of COVID-19 patients. Conclusion: This study suggested an independent association between CKD and in-hospital mortality in COVID-19 patients. Therefore, more intensive surveillance of COVID-19 patients with CKD is to be warranted.

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