QuEChERS-ultra performance liquid chromatography-tandem mass spectrometry for the determination of erythromycin in fishy products(QuEChERS-超高效液相色谱串联质谱法测定水产品中红霉素残留)

YANZhongyong(严忠雍); ZHANGXiaojun(张小军); LIPeipei(李佩佩); FANGYi(方益); YULiang(喻亮); ZHANGShuai(张帅); ZHUYin(祝银); LIQiang(李强)

doi:10.3785/j.issn.1008-9497.2017.03.015

Zhejiang Daxue xuebao. Lixue ban (May 2017)

QuEChERS-ultra performance liquid chromatography-tandem mass spectrometry for the determination of erythromycin in fishy products(QuEChERS-超高效液相色谱串联质谱法测定水产品中红霉素残留)

YANZhongyong(严忠雍),
ZHANGXiaojun(张小军),
LIPeipei(李佩佩),
FANGYi(方益),
YULiang(喻亮),
ZHANGShuai(张帅),
ZHUYin(祝银),
LIQiang(李强)

Affiliations

YANZhongyong(严忠雍): ORCiD; 1.Marine Fisheries Research Institute of Zhejiang, Zhoushan 316021, Zhejiang Province, China( 1.浙江省海洋水产研究所，浙江舟山 316021)
ZHANGXiaojun(张小军): ORCiD; 1.Marine Fisheries Research Institute of Zhejiang, Zhoushan 316021, Zhejiang Province, China( 1.浙江省海洋水产研究所，浙江舟山 316021)
LIPeipei(李佩佩): 1.Marine Fisheries Research Institute of Zhejiang, Zhoushan 316021, Zhejiang Province, China( 1.浙江省海洋水产研究所，浙江舟山 316021)
FANGYi(方益): 1.Marine Fisheries Research Institute of Zhejiang, Zhoushan 316021, Zhejiang Province, China( 1.浙江省海洋水产研究所，浙江舟山 316021)
YULiang(喻亮): 1.Marine Fisheries Research Institute of Zhejiang, Zhoushan 316021, Zhejiang Province, China( 1.浙江省海洋水产研究所，浙江舟山 316021)
ZHANGShuai(张帅): 1.Marine Fisheries Research Institute of Zhejiang, Zhoushan 316021, Zhejiang Province, China( 1.浙江省海洋水产研究所，浙江舟山 316021)
ZHUYin(祝银): 1.Marine Fisheries Research Institute of Zhejiang, Zhoushan 316021, Zhejiang Province, China( 1.浙江省海洋水产研究所，浙江舟山 316021)
LIQiang(李强): 3.Chinese Academy of Fishery Sciences, Beijing 100141, China( 3.中国水产科学研究院，北京 100141)

DOI: https://doi.org/10.3785/j.issn.1008-9497.2017.03.015
Journal volume & issue: Vol. 44, no. 3
pp. 339 – 344

Abstract

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建立了超高效液相色谱串联质谱法测定水产品中的红霉素残留量.样品用改进的QuEChERS（快速、简单、廉价、高效、灵活和安全）进行提取净化，经乙腈快速提取，无水硫酸镁和氯化钠除水后，用N-丙基乙二胺(PSA)净化，液相色谱串联质谱分析测定.在ACQUITY UPLC BEH C18色谱柱上进行分离，采用梯度洗脱，以0.1%甲酸水溶液和甲醇为流动相，电喷雾正离子电离，多反应监测模式，内标法定量.结果表明：红霉素浓度在0.5~50 µg • L-1时具有良好的线性关系，相关系数为0.997 6，定量限为0.3 µg • kg-1，回收率为87.6%~96.1%，相对标准偏差为2.2%~5.3%.本方法操作简易、应用性强，适合水产品中红霉素的常规检测.

Published in Zhejiang Daxue xuebao. Lixue ban

ISSN: 1008-9497 (Print)
Publisher: Zhejiang University Press
Country of publisher: China
LCC subjects: Science: Mathematics: Instruments and machines: Electronic computers. Computer science; Science: Physics
Website: https://www.zjujournals.com/sci/EN/1008-9497/home.shtml

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