Онкогематология (Jan 2017)

MYELODYSPLASTIC/MYELOPROLIFERATIVE DISEASES

  • I. N. Subortseva,
  • A. I. Melikyan

DOI
https://doi.org/10.17650/1818-8346-2016-11-4-8-17
Journal volume & issue
Vol. 11, no. 4
pp. 8 – 17

Abstract

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Chronic myeloid malignancies that have characteristics of both the myelodysplastic and myeloproliferative disorders allocated to myelodysplastic/myeloproliferative diseases (MDS/MPD) group in 2008 World Health Organization classification. This group includes chronic myelomonocytic leukemia, juvenile myelomonocytic leukemia, atypical chronic myeloid leukemia, refractory anemia with ringed sideroblasts and thrombocytosis (RARS-T) and unclassified MDS/MPD. Except RARS-T diseases in this group have similar molecular characteristics and clinical manifestations, which require the study of biology, specific molecular markers, morphological features and a clearer definition of nosology. This review provides information on international guidelines for the diagnosis and treatment of MDS/MPD.

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