Significance of voxel-based morphometry in studying mild cognitive impairments

Abstract

Cognitive impairments are an important medical and socialproblem associated with a high prevalence of this disease in thepopulation. 46% of patients develop dementia within 5 years afterthe diagnosis of mild cognitive impairments (MCIs). Voxelbasedmorphometry (VBM) is a modern neuroimaging techniquewell-proven in studying dementia. VBM in a combinationwith neuropsychological examination of patients enables clarifyingthe genesis of mild cognitive impairments (MCIs) and predictingfurther development of the disease as early as the initialstage of the pathology.

Keywords

• mild cognitive impairments
• vascular cognitive impairments
• voxel-based morphometry
• gray matter
• alzheimer disease
• mixed dementia
• dyscirculatory encephalopathy