A Translation-Aborting Small Open Reading Frame in the Intergenic Region Promotes Translation of a Mg
<sup>2+</sup>
Transporter in
<i>Salmonella</i>
Typhimurium
Eunna Choi,
Yoontak Han,
Shinae Park,
Hyojeong Koo,
Jung-Shin Lee,
Eun-Jin Lee
Affiliations
Eunna Choi
Department of Life Sciences, School of Life Sciences and Biotechnology, Korea University, Seoul, South Korea
Yoontak Han
Department of Life Sciences, School of Life Sciences and Biotechnology, Korea University, Seoul, South Korea
Shinae Park
Department of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon, South Korea
Hyojeong Koo
Department of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon, South Korea
Jung-Shin Lee
Department of Molecular Bioscience, College of Biomedical Science, Kangwon National University, Chuncheon, South Korea
Translation initiation regions in mRNAs that include the ribosome-binding site (RBS) and the start codon are often sequestered within a secondary structure. Therefore, to initiate protein synthesis, the mRNA secondary structure must be unfolded to allow the RBS to be accessible to the ribosome.
