MRI findings of metronidazole neurotoxicity in a pediatric patient with chronic diarrhea

Abstract

Neurotoxicity is a rare side effect of metronidazole therapy. Shown here are findings of metronidazole toxicity in a patient, who received chronic metronidazole as prophylaxis for pseudomembranous colitis following bowel resection as an infant. Findings depicted include increased T2 signal in the dentate nuclei and brainstem. Discontinuing the medication resulted in reversal of the findings. Keywords: Metronidazole neurotoxicity, Pseudomembranous colitis